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Madrid, 30 may (efesalud.com). La doctora Aitana Calvo Ferrándiz y el doctor Guillermo Velasco Oria de Rueda, secretarios científicos de la Sociedad Española de Oncología Médica (SEOM), se trasladan al capitalino parque del Buen Retiro, frondoso y muy sombreado, para hablar de la prevención de uno de los cánceres de piel más mortífero, el melanoma: proceso tumoral que se evita en un 99% de los casos con cremas de protección solar (factor 50) desde la más tierna infancia.

La piel tiene memoria y si no la cuidamos el cáncer se reflejará 20 o 30 años después, cuando se luzcan alrededor de 35 primaveras; aunque el pico de incidencia está en torno a los 55. Solo en España, y cada año, se diagnostican cerca de 4.000 casos de melanoma.

“Si nos exponemos sin más a las radiaciones ultravioleta, principalmente UV-A, que emiten el sol y otras fuentes artificiales, como las lámparas artificiales de las cabinas bronceadoras, tendremos un mayor riesgo de contraer cáncer de piel”, señala el médico oncólogo del Hospital Universitario 12 de Octubre, Guillermo de Velasco.

Nuestro fenotipo determina el nivel de riesgo de padecer un melanoma.

“El riesgo de aparición es 20 veces mayor en personas de raza blanca que en las de raza negra. El riesgo también varía en función del fototipo, que depende a su vez de la capacidad para broncearse, del color de la piel, del color de los cabellos y de los ojos. Las personas con propensión a las quemaduras solares, que casi nunca se broncean, tienen más riesgo”, apunta.

“La prevalencia del melanoma es similar en hombres y mujeres; sin embargo, la localización suele ser diferente: en las mujeres jóvenes predomina en las piernas y en los varones en tronco, cara, cuello y hombros. En niños es raro y suele ser de carácter benigno”, especifica el doctor.

También es más frecuente en las personas que ya tuvieron un melanoma o en personas con antecedentes familiares, algo que sucede en el 10% de los casos. Debemos ser más precavidos todavía si contamos 50 lunares sobre nuestra piel.

Aún así, el signo de sospecha deviene de la regla “ABCDE”.

“A, de asimétrico; B, de bordes irregulares; C, de colores variados; D, de un diámetro superior a los 6 milímetros; y E, de evolución creciente en los últimos meses. El lunar tiene un desarrollo anormal”, describe el doctor Guillermo de Velasco.

El melanoma tiene una incidencia de entre 8 y 9 casos anuales por cada 100.000 habitantes. En un 85% de los casos se cura; en el 15% restante tiene un mal pronóstico.

“Era letal hace apenas cinco o seis años, hasta que aparecieron los nuevos fármacos que permiten niveles de supervivencia prolongados para pacientes con enfermedad metastásica”, expone la doctora Aitana Calvo, médico oncóloga del Hospital Universitario Gregorio Marañón de Madrid.

El tratamiento de la enfermedad depende de la fase en la que se encuentre: si es superficial (1 milímetro) muchas veces es suficiente con una resección; si mide entre 1 y 4 milímetros, la cirugía también podría resolverlo. En fases avanzadas hay que acudir a la inmunoterapia, técnica que estimula las defensas del organismo.

“Dependiendo del tamaño del tumor, se realiza una biopsia del ganglio centinela, para saber si el ganglio más cercano a la tumoración está afectado y es preciso retirar otros ganglios. Después de la cirugía se valora la administración de un tratamiento preventivo con Interferón (IFN) durante un año”, informa.

Sin embargo, comenzó la era de la inmunoterapia con ipilimimumab, un anticuerpo que modula la inmunidad del paciente para que sea ésta la que permita la destrucción del tumor.

Pronto se unieron los anti-PD1 (como nivolumab o pembrolizumab), las combinaciones de agentes que aumentaron la eficacia de los tratamientos.

Además, los tratamientos dirigidos se utilizan en pacientes con determinadas mutaciones como la mutación de BRAF o mutación de c-Kit.

“Los pacientes responden muy rápidamente a los inhibidores de BRAF (vemurafenib/dabrafenib) y su combinación con inhibidores de MEK (trametinib/cobimetinib), o tratamientos como el imatinib”, afirma.

Otros tratamientos novedosos son la administración de virus genéticamente modificados intralesionales.

Los melanomas pueden salir en el intestino, el cerebro o la vagina, aunque el 99 por ciento aparecen en la piel expuesta al sol.

“Por este motivo, lo más importante, como siempre, es la prevención, desde la infancia hasta las edades más avanzada pasando por la adolescencia. Debemos prevenir tanto el melanoma como cualquier otro cáncer de la piel”, concluye la médico oncólogo Aitana Calvo.

Conviene resguardarse del sol entre las doce del mediodía y las seis de la tarde, máxime en verano, y darse crema protectora abundante (factor 50) por todo el cuerpo media hora antes de bajar a la playa o a la piscina o de darnos un chapuzón en el río.

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Bruce Jenner Kim’s step-dad cuts off penis, replaces with artificial vagina

Bruce Jenner: Kim’s step-dad cuts off penis, replaces with artificial vagina?

Bruce Jenner: Kim’s step-dad cuts off penis, replaces with artificial vagina?

Too early to judge fully – just started using it – but it helped me discover Jeff Noon, who’s shaping up to be my new favorite writer. I think it’s going to be a good resource.
[] People wouldn’t need this shit if they had Stummies.
[] Both she, and her book, have far fewer dicks than Reddit would have you believe.
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[] He was sitting next to me on the subway. Asshole doesn’t understand the concept of personal space, had his legs spread out taking up three spots.
[] I think we’d be good friends then :’)
[] Its because their both black.
[] The guy you’re replying too was probably thinking about the planned attack on Panama. They were going to send all the subs to the eastern side and attack the canal locks. The planes weren’t coming back, and even the subs probably weren’t, though they might have had the range.
[] That’s why they suggested boarding last. That way people with legitimate need get the seating they require, and you get what’s left over.
[] This guy nails it. End of thread.
[] Better than a tree any day
[] The Underground Railroad, by Colson Whitehead
[] Society has very obvious ways of socializing youth. Capitalism just reinforces that socialization through marketing. We really need to undo this shit and encourage everyone as an individual to peruse their interests instead of trying to fit people into a mold and shaming them if they don’t fit.
[] Billie Jean
[] My grandfather is being buried in Michigan, I couldn’t afford the flight out there near Grand Rapids, is there anything near there that would help?
[] the ‘grabbing’ of vaginas is what i said isn’t rape. i wasn’t talking about vaginal rape. those two are different. maybe don’t be so quick to jump to conclusions.
[] Why is everyone complaining about their shoes? Do people not try them on and walk around with them first before buying?
[] Back in 1988 I was playing with a synth with headphones in a mall store and played some random notes in a key, not knowing I had triggered some memory storage function.

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Some people clapped and the store manager walked over like he thought I was famous and he nervously started asking what label I recorded for, etc.

I still crack up thinking back to that.
[] I’m Korean and I too prefer the dog
[] These kinds of threads in general are like that: really sweet, but also depressing beyond point when you think about them a bit in comparison to yourself.
[] Wow, that song sucks. The dudes voice is way too nasally, sounds like shit..
[] I’ll try to get Manuel on here or get back to you with an answer.
[] Doesn’t it have something to do with reduced resolution? To my understanding it is harder for the console to display two or more perspectives at once with high res games.
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[] A warm bed and homicide hideout.

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Cottage Cheese
Donald Trump being President is going to be seriously disastrous for America. That and Hilary Clinton is going to be seriously disastrous for America.
Ugh, nothing frustrates me more than the selfish idiot who tries to back into a parking spot in a busy parking lot.
So? Should we disregard the revolution it caused in the industry?
There is a growing contingent of scientists who believe that fatigue is a mental process than we often confuse for a physical one. Considering how many chemicals can make us feel artificially alert without energizing our bodies in any way, I’m inclined to agree.
That’s an ent
I just got a letter from Providence Health saying my plan would be converted from 1000 Gold to 2500 Silver if I “chose to do nothing” by the end of the year.

Of course, when I picked the plan – it wasn’t even listed on their website ( was only listed on healthcare.gov marketplace ) and I called to ask if it was being discontinued at the end of the year since I can’t find it on their website.

This is very common. They re-name the plans, change the coverage, etc. The plans also get re-negotiated with national hospital groups as to what they are willing to accept, what is considered “usual and customary” fees/prices, etc.

It would be a lot easier if they sent out a letter saying “Due to constantly changing costs, variables, and contract negotiations – You can have this exact same coverage, but the price will be $$$ starting 1/1/2017 … If you would like a cheaper plan or different coverage, please visit our website or healthcare.gov and make a choice before 12/15/2016”
Im about to hop on some Warframe after not playing for like 6-7 months. I need to find a good tutorial on everything that has changed.
That sounds like a judicial issue to me mate.
We need a 15 year break from batman movies
/ʒaɪf/
For most people, the cost of a house is not something they can save for the full amount quickly.
TIL Ladybugs had wings under their wings?!
Nobody’s stopping you from trying, I guess. You may not finish though.
All the tall.
2 on the sides and cleanup top.
Fuck that bitch.
Are you seriously saying that this wasn’t completely inappropriate and abusive for a mother to do to her son? So, she sexually molested him because he couldn’t jerk off for a few months? Really? She decided to jerk him off because he was throwing hissyfits? That’s fucked.
i think LVT really went off the rails with this one.
I can eat chocolate, but thinking about the taste makes me nauseous.
i think LVT really went off the rails with this one.

Maybe 20-30% ish get that, but in a lot of cases the vagina tears on it’s own. Most doctors practicing evidence based medicine do not do episiotomies anymore. It was proven to provide no benefit for the mother/child.

The last time I did research on this was about a year ago, and my understanding from the available information is that if the doctor thinks you will tear naturally, they will cut it because a cut will heal faster than a tear.

Do you have newer information that contradicts this?
What did you think it meant by three little pigs went to the market? They were going shopping? Ah childhood innocence – so fleeting
That whole fucking premise is 10/10. After this film horrors just resorted to cheap hauntings and occult
Watt is the fucking man.

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During sexual activities couples at times prefer to use lubricants, both for vaginal and anal intercourses, though there is also a natural lubrication found during penis and vaginal intercourse. We get proof of a man’s sexual excitement through his erect penis, a woman’s excitement shows when her vagina swells, and produces a natural lubricant. At times however, there is no natural lubrication due to the fact that she is not excited or she is apprehensive because it is her first time. At such times it is very important to get artificial lubrication, the common ones are water soluble and oil lubricants. The water soluble lubricants out of the two are the best option as these are the least harmful to the sperms; the oil ones may cause damage to the vagina. So a woman can use them for longer or shorter periods until and unless she is comfortable with it.

Madrid, 29 mar (efesalud.com). La psicóloga y sexóloga, Miren Larrazabal Murillo, nos propone en este vídeoblog dos técnicas, parada-arranque y apretón, para intentar solucionar, o al menos minimizar, la eyaculación precoz, una disfunción sexual muy frecuente que afecta a uno de cada cinco varones y que daña o ha dañado significativamente las relaciones de pareja de más del 40% de la población masculina mundial.

“Durante la práctica sexual los hombres eyaculan sin control antes de realizar la penetración y muchas veces nada más empezar el coito; o, como mucho, apenas alcanzan un minuto y medio de amorío. Tesitura que suele causar graves problemas de pareja al sentir ambos una gran frustración, tanto por el fracaso como por la falta de orgasmo de uno de sus miembros”, dice Miren Larrazabal.

Aunque la satisfacción en las relaciones sexuales de la pareja depende de cada individuo y de sus circunstancias vitales, una investigación de la Universidad Estatal de Pensilvania (EE.UU.), estableció los lapsos promedio de duración de la penetración: “adecuado” (de 3 a 7 minutos); “deseable” (de 7 a 13 minutos); “demasiado corto” (de 1 a 2 minutos); y “demasiado largo” (de 10 a 30 minutos).

Para solucionar esta disfunción, el hombre que padece eyaculación precoz (EP) tiene que implicarse de forma activa en la solución de “su problema”, del mismo modo que lo haría con una enfermedad tan conocida como la hipertensión o la diabetes. Solo un 10% acude al médico.

“El varón debe afrontar esta disfunción sexual en positivo, buscando la ayuda de su pareja y la de un profesional que implemente, entre otras, dos técnicas dirigidas a controlar o retrasar al máximo posible dicha eyaculación: la de la parada y el arranque o la del apretón”, señala.

Primero parada y marcha con ejercicios “a solas” por medio de la autoestimulación, la masturbación. Es un autoaprendizaje. El hombre tiene que controlar su eyaculación y luego practicar los ejercicios con su pareja.

“Cuando el nivel de estimulación es muy alto, sin que las señales de la eyaculación se perciban, se realiza un parón en la masturbación para detener y bajar el nivel de estimulación. En una escala imaginaria de 0 a 10, la parada debe hacerse al llegar a 7 u 8 para descender rápidamente a niveles inferiores. A continuación, vuelta a comenzar y a parar, así dos o tres veces. Luego nos dejamos llevar”, explica.

Con un buen control de la respiración, ejercitándose a menudo, mejor en presencia de la pareja o con su más que interesante ayuda, y perdiendo el miedo a los contratiempos, se puede alcanzar el control voluntario del nivel de excitación, retrasar la eyaculación y conseguir el orgasmo tan deseado de la pareja.

La segunda técnica, de compresión del pene o apretón, se aplica de forma alternativa o complementaria.

“Cesamos la estimulación y apretamos en la base del glande de cuatro a diez segundos hasta que baje la erección, situando el dedo pulgar a la altura del frenillo y los dedos índice y corazón en la cara opuesta del pene. El ejercicio se realiza dos o tres veces hasta que damos rienda suelta al placer del orgasmo”, apunta Miren.

El apretón también se puede ejercer en la base del pene, en la zona de unión con los testículos, lo que permite no retirar el pene de la vagina durante la penetración.

“Jugad y jugad con estos ejercicios hasta que la eyaculación esté totalmente dominada. También se pueden utilizar anos o vaginas artificiales a modo de cabina de pruebas, como si se tratara de un piloto de aeronaves. De igual forma que se aprende a volar en tierra, se aprende poco a poco a controlar la eyaculación sin relación coital”.

El objetivo final de estos ejercicios de terapia sexual se centran en mantener un nivel alto de excitación sin la necesidad imperiosa de eyacular.

“Y si no sois capaces de superar esta disfunción sexual por vuestra cuenta o con la ayuda del ser amado -indica la psicóloga y sexóloga clínica- acudid a un profesional, quien mejorará, sin duda, vuestro control eyaculatorio y, de paso, vuestra relación de pareja”.

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Let’s save the oldest sister’s vagina now!
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PRINCETON, NEW JERSEY — Ted Cruz’s college roommate outs him again, this time sharing a little TMI about the GOP candidate’s extra curricular activities.

According to former roommate, screenwriter and film director Craig Mazin, Cruz was familiar with self pleasuring.

“Ted Cruz thinks people don’t have a right to ‘stimulate their genitals,'” Mazin wrote on Twitter. “I was his college roommate. This would be a new belief of his.”

The tweet followed the publication of a recent article by “Mother Jones,” titled “The Time Ted Cruz Defended a Ban on Dildos.” The article referred to a decade-old case Cruz was tasked with while serving as Texas’ solicitor general from 2003 to 2008.

The office fought to defend a ruling in the state that found selling sex toys was not protected by the Constitution. Namely, the legislation banned the sale of masturbatory items like “dildos, artificial vaginas and other obscene devices,” on the grounds that “there is no substantive-due-process right to stimulate one’s genitals for non-medical purposes unrelated to procreation or outside of an interpersonal relationship.”

Cruz’s office ultimately lost the case with the court siding with local business owners. The office filed a brief for a full appeals court hearing but decided not to bring the case to the Supreme court.

Mazin, who has penned sequels to “Scary Movie” and “The Hangover,” has been tweeting about Cruz for months. A majority of his rants have been about how much he loathes the presidential hopeful, calling him a liar on most occasions.

Mazin has even shared, “Ted has jerked off to porn a million times.”

And when asked a fellow tweeter posted, “Apparently your roommate wants govt. To ban sex toys. Please tell us he had a dildo stashed under his pillow,” Mazin had to reply. He wrote, “Ted Cruz did not have a dildo stashed under his pillow. Ted Cruz slept on top of his pillow.”

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